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This inhibition relieves the suppression of ULK1, a key initiator of autophagy, leading to the formation of autophagosomes [64]

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Gene 533:469476 Alves E, Binienda Z, Carvalho F, Alves CJ, Fernandes E, de Lourdes Bastos M, Tavares MA, Summavielle T (2009) Acetyl-l-carnitine provides effective in vivo neuroprotection over 3,4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain

This hypothesis can explain the observation that hyperbaric oxygen treatment lengthens survival of diquat-treated selenium-deficient rats (Burk and Lane 1983)

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Autophagy inhibition reduces chemoresistance and tumorigenic potential of human ovarian cancer stem cells